Innovative targets in medicinal chemistry

Introduction

Medicinal chemistry continuously evolves in response to emerging healthcare needs and advancements in scientific understanding. This special issue explores the current landscape of innovative targets in medicinal chemistry, highlighting the quest for novel therapeutic avenues. From traditional drug targets such as enzymes and receptors to emerging targets like protein-protein interactions and DNA/RNA, this abstract delves into the diverse spectrum of molecular entities under investigation. It discusses the rationale behind targeting these novel entities, emphasizing their potential to address unmet medical needs and overcome challenges associated with existing therapies. Additionally, the abstract elucidates cutting-edge methodologies and technologies driving target discovery and validation, including computational modelling, high-throughput screening, and structure-based drug design. By shedding light on the dynamic landscape of medicinal chemistry, this special issue aims to inspire further exploration and innovation in the field of effective treatments for diverse diseases.

Keywords

Medicinal chemistry, innovative targets, high-throughput screening, structure-based drug design, drug targets

Sub-topics

1. Novel therapies for infectious diseases
2. Innovations in cancer treatment
3. Structure-based drug design
4. Biomarkers for disease progression and therapy response
5. AI-driven lead optimization