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Current Pharmaceutical Design

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ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

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Review Article

Rheological Characterization of Pharmaceutical and Cosmetic Formulations for Cutaneous Applications

Author(s): Nicolas Huang*

Volume 25, Issue 21, 2019

Page: [2349 - 2363] Pages: 15

DOI: 10.2174/1381612825666190716110919

Price: $65

Abstract

Rheology, the study of the flow and deformation of matter, can be a daunting subject for scientists new to this field. However, its importance in characterization and optimization of formulations is indisputable. This review intends to provide basic and practical rheological notions in order to better understand the key concepts such as shear stress, shear rate, viscosity, elastic and viscous moduli and phase angle, and learn to distinguish between flow and oscillation experiments. We will explain the different rheological behaviors such as shear thinning, thixotropy or viscoelasticity. Throughout this review, these concepts will be illustrated with examples taken from pharmaceutical and cosmetic formulations. Rheology is a broad subject and this review does not intend to be comprehensive, but rather to be concise and pedagogical.

Keywords: Rheology, viscosity, viscoelasticity, formulation, pharmaceutics, cosmetics.

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