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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Applications of Peptide Mimetics in Cancer

Author(s): V. Apostolopoulos, J. Matsoukas, M. Plebanski and T. Mavromoustakos

Volume 9, Issue 4, 2002

Page: [411 - 420] Pages: 10

DOI: 10.2174/0929867023370969

Price: $65


The development of a vaccine for cancer has been difficult compared to the effective vaccines of infectious diseases. Most tumor antigens are not entirely foreign and are expressed on normal tissues, thus, making it difficult to induce strong immune responses against self antigens. A peptide mimic, however, may have the potential to generate greater immune responses than those induced to self peptides. In this review we discuss applications of peptide mimcs for cancer immunotherapy which may ultimately prove useful in humans.

Keywords: Peptide Mimetics, immunotherapy, anti-idiotypic antibodies, lipooligosaccharide

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