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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Anticoagulation after Iliofemoral Vein Stenting - Old Versus New

Author(s): Anja B. Drebes* and Neil H. Davies

Volume 24 , Issue 38 , 2018

Page: [4525 - 4533] Pages: 9

DOI: 10.2174/1381612825666181226151114

Price: $65


In recent years, there has been an increasing interest in endovascular iliofemoral vein stenting to prevent/ alleviate symptoms related to proximal venous outflow obstruction. Maintaining long-term stent patency is one of the main challenges, and risk factors for the development of re-thrombosis are not well understood. Published data on the safety and efficacy of the procedure predominantly come from cohort studies mainly focusing on mechanical aspects relating to stent placement and flow. Aetiology of thrombus formation and thrombotic tendencies of patients due to underlying medical conditions are not captured well or linked to clinical outcomes, and the impact of choice and length of antithrombotic therapy have not been specifically investigated. Here, we review different procedure-related factors and patient characteristics that might increase the risk of re-thrombosis and the utility of antithrombotic treatment options currently available.

Keywords: Venous stent, anticoagulation, iliofemoral vein thrombosis, direct oral anticoagulants, postthrombotic syndrome, aetiology.

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