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Review Article

新的结核病候选疫苗

卷 27, 期 31, 2020

页: [5095 - 5118] 页: 24

弟呕挨: 10.2174/0929867326666181126112124

价格: $65

摘要

肺结核排在艾滋病之前，是每年影响和杀死许多人的第九大致死原因。药物的疗效受到耐多药(MDR)和广泛耐药(XDR)等一系列问题的制约。与此同时，已有90多年历史的唯一获批疫苗卡介苗(卡介苗)的效力不够。因此，开发新的结核病预防和免疫治疗疫苗至关重要。本文综述了结核病流行情况、免疫系统对结核病的反应以及结核病疫苗的研究和开发的最新进展。本文介绍了几种正在进行临床试验的疫苗以及基于ram的候选疫苗。

关键词: 结核病，疫苗，肪阿拉伯甘露糖，免疫治疗，反应，LAM基候选药物。

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