Abstract
A facile, efficient, additive-free and eco-friendly protocol for the synthesis of (E)-vinyl isobutyronitriles via Fe(III)-catalyzed decarboxylative cross-coupling of cinnamic acids and AIBN (azodiisobutyronitrile) has been developed. The presented methodology offers several advantages such as easy accessibility and stability of substrates, inexpensive catalyst and simple post-treatment procedure.
Keywords: Decarboxylative cross-coupling, cinnamic acids, AIBN, vinyl isobutyronitriles, additives, heterocycle.
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