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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Current Scenario in Structure and Ligand-Based Drug Design on Anti-colon Cancer Drugs

Author(s): Lakshmanan Loganathan and Karthikeyan Muthusamy*

Volume 24 , Issue 32 , 2018

Page: [3829 - 3841] Pages: 13

DOI: 10.2174/1381612824666181114114513

Price: $65


Worldwide, colorectal cancer takes up the third position in commonly detected cancer and fourth in cancer mortality. Recent progress in molecular modeling studies has led to significant success in drug discovery using structure and ligand-based methods. This study highlights aspects of the anticancer drug design. The structure and ligand-based drug design are discussed to investigate the molecular and quantum mechanics in anti-cancer drugs. Recent advances in anticancer agent identification driven by structural and molecular insights are presented. As a result, the recent advances in the field and the current scenario in drug designing of cancer drugs are discussed. This review provides information on how cancer drugs were formulated and identified using computational power by the drug discovery society.

Keywords: Colorectal cancer, structure-ligand based screening, drug designing, anti-colon cancer drugs, chronic degenerative disease (CDD).

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