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Current Medical Imaging


ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

General Research Article

The Value of Low-dose Prospective Dual-energy Computed Tomography with Iodine Mapping in the Diagnosis of Gastric Cancer

Author(s): Lifeng Wang, Xingxing Jin, Zhenguo Qiao*, Bin Xu and Jiaqing Shen*

Volume 16, Issue 4, 2020

Page: [433 - 437] Pages: 5

DOI: 10.2174/1573405614666181023114051

open access plus


Objectives: This study investigated the radiation dose and value of prospective dualenergy computed tomography (DECT) in the diagnosis of gastric cancer.

Methods: Sixty patients scheduled for computed tomography (CT) for preoperative staging were divided into two groups. Thirty patients (Group A) underwent a single contrast-enhanced abdominal CT acquisition using a dual-source mode (100 kV/140 kV). Weighted average images of the two-kilovolt acquisitions and iodine maps were created. The remaining 30 patients underwent a standard CT scan (Group B). Two observers performed a blinded read of the images for gastric lesions, evaluating the image quality and recording effective dose.

Results: During the blinded read, observers found 90% (27/30) of the cancers in both groups. The mean imaging quality scores were 2.1±0.9 for Group A, and 2.3±1.1 for Group B. The effective mean doses were 6.59±0.59 mSv and 25.86±0.44 mSv for Groups A and B, respectively. Compared with the control group (B), the imaging quality in the low-dose group decreased a little, but the radiation dose substantially decreased by 74.6%.

Conclusion: The new DECT technique is valuable for examining gastric cancer patients. The dualkV scan mode can substantially reduce radiation dose while preserving good diagnostic image quality.

Keywords: Computed tomography (CT), radiation dose, diagnosis, gastric cancer, patients, DECT.

Graphical Abstract
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