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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Single Probiotic versus Multiple Probiotics - A Debate On Current Scenario for Alleviating Health Benefits

Author(s): Siva K. Korada, Nagendra S. Yarla, Vijayendra Mishra, Mohamed A. Daim, Bechan Sharma, Ashraf GM, Reggi R., Palmery M, Ilaria Peluso and Mohammad A. Kamal*

Volume 24 , Issue 35 , 2018

Page: [4150 - 4153] Pages: 4

DOI: 10.2174/1381612824666181012124136

Price: $65


Strain, dose, duration, validated clinical trial studies and scientific substantiation of health claims are needed in order to define a successful probiotic. In particular, the potency of probiotic differs from strain to strain. In this view, we aimed to know whether the single strain or multi-strain construct is more beneficial. We found that the studies were still under debate and mechanisms remain sometimes unclear. No conclusion can be made based on the strain experimentation. Safety data and significant statistical results for efficacy via well-controlled clinical trials are needed.

Keywords: Probiotics, health benefits, single strain, safety recommendation, multiple probiotics, gut microbiota.

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