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Current Nutrition & Food Science

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ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

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Research Article

Curry Leaf and its Antioxidant Potential: A Systematic Study to Enhance its Activity in Aqueous Medium

Author(s): Deepa Kumari, Tamanna Mallick, Abhijit Karmakar, Samiran Mondal, Sreeparna Das* and Naznin Ara Begum*

Volume 16, Issue 3, 2020

Page: [323 - 332] Pages: 10

DOI: 10.2174/1573401314666181002142757

Price: $65

Abstract

Background: We have done a systematic study on the antioxidant activity of the methanol and petroleum ether (60-80°C) extracts (MEC and PEC respectively) of Curry leaves (Murraya koenigii Spreng. Family: Rutaceae) using various in-vitro chemical methods.

Methods: Both of these two extracts were found to be highly efficient in the formation of Ag and Au nanoparticles. So, we have explored their ability to form the nanoparticles to study their antioxidant activity. In all the assay systems, MEC showed higher activity over PEC in aqueous medium. This may be due to the higher solubility of MEC and its active components, like polyphenols and flavonoids in the aqueous medium. PEC contains lesser amount of these water soluble active components but PEC was rich in carbazole types of alkaloids which are hydrophobic in nature. So, to enhance the antioxidant activity of PEC and its carbazole constituents, like 2-hydroxy carbazole and mahanimbine, we have encapsulated these in the biopolymeric matrix of the mucilage isolated from an edible vegetable, Abelmoschus esculentus L. (commonly known as Lady's finger, family: Malvaceae).

Result: It was interesting to note that, PEC and its carbazole compounds showed better antioxidant activity (ferrous ion chelation and ferric reducing antioxidant activity) in aqueous medium after this encapsulation process.

Conclusion: The protocols used in the present study were very simple and can be implemented in any lab set-up. In future, this work can be extended to evaluate antioxidant potentials of other plant based materials.

Keywords: Abelmoschus esculentus L., antioxidant activity, curry leaves, encapsulation, lady's finger, Murraya koenigii Spreng.

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[1]
Ojo OA, Akintayo CO. Assessment of antioxidant activity of Ficus asperifolia Miq aqueous extract-in vitro studies. J Phytopharmacol 2014; 3: 16-21.
[2]
Borrelli F, Borbone N, Capasso R, et al. New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus. Planta Med 2004; 70(7): 652-6.
[http://dx.doi.org/10.1055/s-2004-827190] [PMID: 15254858]
[3]
Borbone N, Borrelli F, Montesano D, et al. Identification of a new sesquiterpene polyol ester from Celastrus paniculatus. Planta Med 2007; 73(8): 792-4.
[http://dx.doi.org/10.1055/s-2007-981543] [PMID: 17599283]
[4]
Borrelli F, Borbone N, Capasso R, et al. Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum. J Ethnopharmacol 2009; 122(3): 434-8.
[http://dx.doi.org/10.1016/j.jep.2009.02.003] [PMID: 19429308]
[5]
Nayak A, Mandal S, Banerji A, et al. Review on chemistry and pharmacology of Murraya koenigii Spreng (Rutaceae). J Chem Pharm Res 2010; 2: 286-99.
[6]
Ningappa MB, Dinesha R, Srinivas L. Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extracts. Food Chem 2008; 106: 720-8.
[http://dx.doi.org/10.1016/j.foodchem.2007.06.057]
[7]
Roy N, Laskar RA, Sk I, Kumari D, et al. A detailed study on the antioxidant activity of the stem bark of Dalbergia sissoo Roxb., an Indian medicinal plant. Food Chem 2011; 126: 1115-11210.
[http://dx.doi.org/10.1016/j.foodchem.2010.11.143]
[8]
Chang C, Yang M, Wen H, et al. Estimation of total flavonoid content in propolis by two complementary colorimetric methods. Yao Wu Shi Pin Fen Xi 2002; 10: 178-82.
[9]
Mcdonald S, Prenzler PD, Autolovich M, et al. Phenolic content and antioxidant activity of olive extracts. Food Chem 2001; 73: 73-84.
[http://dx.doi.org/10.1016/S0308-8146(00)00288-0]
[10]
Koleva II, van Beek TA, Linssen JPH, de Groot A, Evstatieva LN. Screening of plant extracts for antioxidant activity: a comparative study on three testing methods. Phytochem Anal 2002; 13(1): 8-17.
[http://dx.doi.org/10.1002/pca.611] [PMID: 11899609]
[11]
Oyaizu M. Studies on products of browning reactions: antioxidative activities of products of browning reaction prepared from glucosamine. Jpn J Nutr 1984; 44: 629-32.
[12]
Dinis TCP, Maderia VM, Almeida LM. Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch Biochem Biophys 1994; 315(1): 161-9.
[http://dx.doi.org/10.1006/abbi.1994.1485] [PMID: 7979394]
[13]
Scampicchio M, Wang J, Blasco AJ, Sanchez Arribas A, Mannino S, Escarpa A. Nanoparticle-based assays of antioxidant activity. Anal Chem 2006; 78(6): 2060-3.
[http://dx.doi.org/10.1021/ac052007a] [PMID: 16536447]
[14]
Wang J, Zhou N, Zhu Z, Huang J, Li G. Detection of flavonoids and assay for their antioxidant activity based on enlargement of gold nanoparticles. Anal Bioanal Chem 2007; 388(5-6): 1199-205.
[http://dx.doi.org/10.1007/s00216-007-1295-y] [PMID: 17479255]
[15]
Woolfe ML, Chaplid MF, Otchere G. Studies on the mucilages extracted from okra fruits (Hibiscus esculentus L.) and baobab leaves (Adansonia digitata L.). J Sci Food Agric 1917; 28: 519-29.
[http://dx.doi.org/10.1002/jsfa.2740280609]
[16]
Das J, Das S, Samadder A, Bhadra K, Khuda-Bukhsh AR. Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells. Eur J Pharm Sci 2012; 47(2): 313-24.
[http://dx.doi.org/10.1016/j.ejps.2012.06.018] [PMID: 22771545]
[17]
Fattorea M, Montesanob D, Paganoc E, et al. Carotenoid and flavonoid profile and antioxidant activity in “pomodorino vesuviano” tomatoes. J Food Compos Anal 2016; 53: 61-8.
[http://dx.doi.org/10.1016/j.jfca.2016.08.008]
[18]
Rocchetti G, Lucini L, Chiodelli G, et al. Impact of boiling on free and bound phenolic profile and antioxidant activity of commercial gluten-free pasta. Food Res Int 2017; 100(Pt 2): 69-77.
[http://dx.doi.org/10.1016/j.foodres.2017.08.031] [PMID: 28888460]
[19]
Rocchetti G, Chiodelli G, Giuberti G, et al. UHPLC-ESI-QTOF-MS profile of polyphenols in Goji berries (Lycium barbarum L.) and its dynamics during in vitro gastrointestinal digestion and fermentation. J Funct Foods 2018; 40: 564-72.
[http://dx.doi.org/10.1016/j.jff.2017.11.042]
[20]
Whistler RL, Barkalow DG, et al. BeMiller JN. Aloea, chia, flax seed, okra, psyllium seed, quince seed, and tamarin gums. In: Industrial Gums, Whistler RL, BeMiller JN (Eds). Academic Press: New York 1993; pp. 227-56.
[21]
Ofoefule SI, Chukwu AN, Anayakoha A, et al. Application of Abelmoschus esculentus in solid dosage forms 1: use as binder for poorly water soluble drug. Indian J Pharm Sci 2001; 63: 234-8.
[22]
Kumar R, Patil MB, Patil SR, et al. Evaluation of Abelmoschus esculentus mucilage as paracetamol suspension. Int J Pharm Tech Res 2009; 1: 658-65.
[23]
Lengsfeld C, Titgemeyer F, Faller G, Hensel A. Glycosylated compounds from okra inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Agric Food Chem 2004; 52(6): 1495-503.
[http://dx.doi.org/10.1021/jf030666n] [PMID: 15030201]
[24]
Gemede HF, Ratta N, Haki GD, et al. Nutritional quality and health benefits of okra (Abelmoschus esculentus): a review. J Food Process Technol 2015; 6: 458-63.
[http://dx.doi.org/10.4172/2157-7110.1000458]
[25]
Chen X, Zou LQ, Niu J, Liu W, Peng SF, Liu CM. The stability, sustained release and cellular antioxidant activity of curcumin nanoliposomes. Molecules 2015; 20(8): 14293-311.
[http://dx.doi.org/10.3390/molecules200814293] [PMID: 26251892]
[26]
Das S, Alam MN, Batuta S, et al. Exploring the efficacy of Basella alba mucilage towards the encapsulation of the hydrophobic antioxidants for their better performance. Process Biochem 2017; 61: 178-88.
[http://dx.doi.org/10.1016/j.procbio.2017.06.022]

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