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Current Pharmaceutical Biotechnology


ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Growth Factor Delivery to Re-Engineer Periodontal Tissues

Author(s): Orasa Anusaksathien and William V. Giannobile

Volume 3, Issue 2, 2002

Page: [129 - 139] Pages: 11

DOI: 10.2174/1389201023378391

Price: $65


Repair of tooth-supporting structures destroyed by the chronic inflammatory disease periodontitis is a major goal of oral therapy. The field of tissue engineering combines materials science and biology to repair tissues and organs. Periodontal tissue engineering has been achieved with limited success by the utilization of guiding tissue (cell occlusive) membranes and bone grafting techniques. Over the past decade investigators have begun to utilize signaling molecules such as growth factors to restore lost tooth support due to periodontitis, the most common bone disease affecting humans. This review will provide information on the status of growth factor therapies being applied in periodontology to treat advanced alveolar bone loss.

Keywords: igfs, periodontal, growth factor, gfs, gtr

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