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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

The Role of Protease Inhibition with Emphasis on the Effects of Inflammation and Vascular Immune Phenomena

Author(s): T. V. Bilfinger and George B. Stefano

Volume 8, Issue 7, 2002

Page: [505 - 509] Pages: 5

DOI: 10.2174/1381612023395763

Price: $65


This review discusses the role of protease inhibition with emphasis on the effects of inflammation and vascular immune phenomena in non-immunocompromised hosts. A vast body of knowledge elucidating the role of protease inhibition and hemostasis has accumulated in recent years. The two subjects are intimately linked, but the focus of this review is limited to the anti-inflammatory effects of protease inhibitors. In light of the particular expertise of the present authors, this review will focus on human studies and often cite work related to open-heart surgery, since in recent years this is the area in which a large effort has been concentrated worldwide.

Keywords: protease inhibition, inflammation, protease inhibitors, Inflammatory processes

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