Abstract
Glycans expressed on the forefront surface of cells participate in many key biological processes via forming various glycoconjugates. The recognition of complex glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. As the increasing accessibility of glycoconjugates, it has been widely applied in the field of drug delivery. This review particularly refers to the constitutive glycoconjugates of receptor-mediated binding of glycoprotein, glycolipids and glycopeptides for cell-selective drug delivery, in order to broaden the future therapeutic scope of drug delivery system and effective cancer therapy.
Keywords: Drug delivery, glycoconjugates, glycolipid, glycopeptide, glycoprotein, targeting.
Mini-Reviews in Medicinal Chemistry
Title:Biomedical Applications of Glycoconjugates
Volume: 18 Issue: 18
Author(s): Fei Ding and Yongmin Zhang*
Affiliation:
- Wuhan Economic and Technological Development Zone, Institute for Interdisciplinary Research, Jianghan University, Wuhan 430056,China
Keywords: Drug delivery, glycoconjugates, glycolipid, glycopeptide, glycoprotein, targeting.
Abstract: Glycans expressed on the forefront surface of cells participate in many key biological processes via forming various glycoconjugates. The recognition of complex glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. As the increasing accessibility of glycoconjugates, it has been widely applied in the field of drug delivery. This review particularly refers to the constitutive glycoconjugates of receptor-mediated binding of glycoprotein, glycolipids and glycopeptides for cell-selective drug delivery, in order to broaden the future therapeutic scope of drug delivery system and effective cancer therapy.
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Cite this article as:
Ding Fei and Zhang Yongmin*, Biomedical Applications of Glycoconjugates, Mini-Reviews in Medicinal Chemistry 2018; 18 (18) . https://dx.doi.org/10.2174/1389557518666180518083427
DOI https://dx.doi.org/10.2174/1389557518666180518083427 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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