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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Recent Advances in Magnetic Nanoparticle-based Molecular Probes for Hepatocellular Carcinoma Diagnosis and Therapy

Author(s): Qi Zhang, Sudan Wang, Ruirui Qiao*, Michael R. Whittaker, John F. Quinn, Thomas P. Davis and Hongjun Li*

Volume 24 , Issue 21 , 2018

Page: [2432 - 2437] Pages: 6

DOI: 10.2174/1381612824666180516111939

Price: $65

Abstract

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, leading to the second most likely cause of cancer-related deaths. Medical imaging is crucial in clinic for HCC screening and diagnosis. Due to the relatively high special resolution and excellent sensitivity, magnetic resonance imaging (MRI) by using magnetic nanoparticle-based contrast agents has been used so far in HCC imaging and staging, demonstrating great potential and promising in vivo applications. This review focuses on the use of different magnetic nanoparticles for construction of HCC nanoprobes for MR imaging and theranostic purpose.

Keywords: Magnetic nanoparticle, MRI, hepatocellular carcinoma, molecular imaging, cancer, diagnosis.


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