Progressive Supranuclear Palsy: Neuropsychopathological, Therapeutical and Bioethical Aspects

Title:Progressive Supranuclear Palsy: Neuropsychopathological, Therapeutical and Bioethical Aspects

Volume: 15 Issue: 10

Author(s): Ignazio Vecchio, Cristina Tornali, Giulia Malaguarnera, Nicola Luigi Bragazzi and Michele Malaguarnera*

Affiliation:

• Research Center ,Italy

Keywords: Progressive supranuclear palsy, tonopathy, movement disorders, bioethics, clinical ethics, cognitive disease.

Abstract: The progressive supranuclear palsy is a progressive neurodegenerative disease characterized by Parkinsonism, oculomotor abnormalities, early postural instability and cognitive impairment. Neurodegeneration in PSP is associated with tau protein, but the mechanisms by which tau abnormalities lead to cell dysfunction and death are not well understood.

Neuro-behavioural problems related to the fear and loss of autonomy can determinate many bioethical implications. Careful planning involving patients’ families, academic and industry researchers were necessary to ensure improvement in quality of life.

Cite this article as:

Vecchio Ignazio , Tornali Cristina , Malaguarnera Giulia , Bragazzi Luigi Nicola and Malaguarnera Michele *, Progressive Supranuclear Palsy: Neuropsychopathological, Therapeutical and Bioethical Aspects, Current Alzheimer Research 2018; 15(10) . https://dx.doi.org/10.2174/1567205015666180507111958