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Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

Author(s): Justine P.R. Oliveira*, H. Ivan Melendez-Ortiz, Emilio Bucio, Patricia Terra Alves, Mayara Ingrid Sousa Lima, Luiz Ricardo Goulart, Monica B. Mathor, Gustavo H.C. Varca and Ademar B. Lugao

Volume 18, Issue 4, 2018

Page: [256 - 274] Pages: 19

DOI: 10.2174/1568026618666180410151518

Price: $65


Safety and biocompatibility assessment of biomaterials are themes of constant concern as advanced materials enter the market as well as products manufactured by new techniques emerge. Within this context, this review provides an up-to-date approach on current methods for the characterization and safety assessment of biomaterials and biomedical devices from a physical-chemical to a biological perspective, including a description of the alternative methods in accordance with current and established international standards.

Keywords: Biomaterials, Physico-chemical characterization, Biocompatibility, In silico, In vitro, In vivo, Ex vivo, Alternative methods, International standards.

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