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Current Cancer Therapy Reviews

Editor-in-Chief

ISSN (Print): 1573-3947
ISSN (Online): 1875-6301

Review Article

Stereotactic Body Radiation Therapy in Head and Neck Squamous Cell Carcinoma: Science or Art?

Author(s): Rashi Garg and Omar Mahmoud*

Volume 14 , Issue 1 , 2018

Page: [68 - 74] Pages: 7

DOI: 10.2174/1573394714666180122143310

Price: $65

Abstract

Background: Stereotactic body radiotherapy (SBRT) or radiosurgery has emerged as a viable highly precise technique that delivers a hypofractionated radiotherapy regimen with a high biologic effective dose. In addition to patient convenience, this dose is thought to provide acceptable local control while keeping toxicity to a minimum due to the typical small target size. The aims of this paper are to review recent outcomes with the application of SBRT in the management of head and neck cancer.

Methods: Research and online content related to head and neck cancer SBRT were reviewed focusing on dose fractionation schedules, incorporation of systemic therapy and long term toxicity.

Results: SBRT technique provided convenient precise approach in the management of primary as well as recurrent head and neck cancer with adequate local control rates and tolerable long term toxicity profile.

Conclusion: The use of stereotactic body radiotherapy is still evolving and multiple studies are needed to optimize the dose fractionation of SBRT and its integration with systemic therapy.

Keywords: Streotactic Body Radiotherapy (SBRT), Head and Neck Cancer (HNC), toxicity, hypofractionation, Squamous Cell Carcinoma (SCC), carcinoma.

Graphical Abstract

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