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Current Nutrition & Food Science


ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Review Article

Vitamin B12: From Deficiency to Biotechnological Solution

Author(s): Ramona Massoud, Kianoush Khosravi-Darani*, Seyed M.H. Bagheri, Amir M. Mortazavian and Sara Sohrabvandi

Volume 15, Issue 4, 2019

Page: [318 - 326] Pages: 9

DOI: 10.2174/1573401314666171207145429

Price: $65


Vitamin B12 production by using propionibacteria and enriching food to produce functional foods is an important subject for researches. Some microorganisms have the potential to produce a wide range of components that are health promoting for human. Among them Propionibacteria has been identified as an effective producer of vitamin B12 and anti-microbial compounds such as propionic acid for decades. In this study at first, the structure, health beneficial effects and properties of vitamin B12 as well as scaled up production of vitamin are mentioned. Then biotechnological strategy is described as a solution to overcome vitamin deficiency and production of functional food. Finally, the specification of propionibacteria and its growth condition as well as bacterium ability to produce some other interesting metabolite in human food as byproduct are discussed.

Keywords: Biosynthesis, functional food, health effects, propionibacteria, vitamin B12, anti-microbial compounds.

Graphical Abstract
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