Abstract
Hypertension can be referred to as modern scourge in 2017 and although, it seems that an improvement has been done during the passage of time, the full treatment still remains an unmet achievement for clinicians. Hypertension incidence in Mediterranean countries, especially Greece and Turkey, seems to be increasing irrespective of the expected protective effect of Mediterranean diet. The changed lifestyle and dietary habits of both populations led to advanced cardiovascular events and arteriosclerosis both of which are linked with high blood pressure. From statistic aspect, as in this work reviewed, it has been found out that gender, age, sociodemographic characteristics and geographical location could promote the hypertension prevalence. Given the above, as well as the fact that the current pharmaceutical formulations do not present the optimal results on hypertension management, summing up the ongoing research on hypertension field is in high demand. Consequently, the development of novel solutions for high blood pressure management either with new synthesized drugs or fascinated drug delivery systems is required. Moreover, adopting healthy lifestyle and diet also plays a crucial role against hypertension. This review is aimed at assisting researchers working on hypertension management by summarizing update guidelines, various case reports describing hypertension related with other diseases, current medications and newly synthesized drug delivery systems recently found in literature.
Keywords: Hypertension, new antihypertensive formulations, epidemiology, Mediterranean countries, guidelines, treatment.
Current Pharmaceutical Design
Title:Hypertension in 2017: Update in Treatment and Pharmaceutical Innovations
Volume: 23 Issue: 44
Author(s): Mehmet Evren Okur, Ioannis D. Karantas, Neslihan Ustundag Okur and Panoraia I. Siafaka*
Affiliation:
- Department of Pharmaceutical Technology, Istanbul Medipol University, School of Pharmacy, Beykoz, 34810, Istanbul,Turkey
Keywords: Hypertension, new antihypertensive formulations, epidemiology, Mediterranean countries, guidelines, treatment.
Abstract: Hypertension can be referred to as modern scourge in 2017 and although, it seems that an improvement has been done during the passage of time, the full treatment still remains an unmet achievement for clinicians. Hypertension incidence in Mediterranean countries, especially Greece and Turkey, seems to be increasing irrespective of the expected protective effect of Mediterranean diet. The changed lifestyle and dietary habits of both populations led to advanced cardiovascular events and arteriosclerosis both of which are linked with high blood pressure. From statistic aspect, as in this work reviewed, it has been found out that gender, age, sociodemographic characteristics and geographical location could promote the hypertension prevalence. Given the above, as well as the fact that the current pharmaceutical formulations do not present the optimal results on hypertension management, summing up the ongoing research on hypertension field is in high demand. Consequently, the development of novel solutions for high blood pressure management either with new synthesized drugs or fascinated drug delivery systems is required. Moreover, adopting healthy lifestyle and diet also plays a crucial role against hypertension. This review is aimed at assisting researchers working on hypertension management by summarizing update guidelines, various case reports describing hypertension related with other diseases, current medications and newly synthesized drug delivery systems recently found in literature.
Export Options
About this article
Cite this article as:
Okur Evren Mehmet , Karantas D. Ioannis, Okur Ustundag Neslihan and Siafaka I. Panoraia*, Hypertension in 2017: Update in Treatment and Pharmaceutical Innovations, Current Pharmaceutical Design 2017; 23 (44) . https://dx.doi.org/10.2174/1381612823666170927123454
DOI https://dx.doi.org/10.2174/1381612823666170927123454 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
"Tuberculosis Prevention, Diagnosis and Drug Discovery"
The Nobel Prize-winning discoveries of Mycobacterium tuberculosis and streptomycin have enabled an appropriate diagnosis and an effective treatment of tuberculosis (TB). Since then, many newer diagnosis methods and drugs have been saving millions of lives. Despite advances in the past, TB is still a leading cause of infectious disease mortality ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Emerging and re-emerging diseases
Faced with a possible endemic situation of COVID-19, the world has experienced two important phenomena, the emergence of new infectious diseases and/or the resurgence of previously eradicated infectious diseases. Furthermore, the geographic distribution of such diseases has also undergone changes. This context, in turn, may have a strong relationship with ...read more
Melanoma and Non-Melanoma Skin Cancer Treatment: Standard of Care and Recent Advances
In this thematic issue, we aim to provide a standard of care of the diagnosis and treatment of melanoma and non-melanoma skin cancer. The editor will invite authors from different countries who will write review articles of melanoma and non-melanoma skin cancers. The Diagnosis, Staging, Surgical Treatment, Non-Surgical Treatment all ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Actual Knowledge of Systemic Inflammation Reaction During Cardiopulmonary Bypass
Recent Patents on Cardiovascular Drug Discovery Pharmacologic Therapy for Cardiovascular Risk Reduction in Patients with the Metabolic Syndrome
Current Pharmaceutical Design Epoxyeicosatrienoic Acid Analogs and Vascular Function
Current Medicinal Chemistry Crofelemer: In HIV Associated Diarrhea and Secretory Diarrhea - A Patent Perspective
Recent Patents on Anti-Infective Drug Discovery Central Blood Pressure and Prediction of Cardiovascular Events
Current Hypertension Reviews Liver and Pancreatic Disease in Cystic Fibrosis: Clinics and Drug Therapy
Clinical Immunology, Endocrine & Metabolic Drugs (Discontinued) Polypoidal Choroidal Vasculopathy: Recent Advances in Therapy
Current Drug Targets Development and Validation of a Sensitive HPLC-MS/MS-ESI Method for Determination of Febuxostat: Application to Pharmacokinetic Study
Current Analytical Chemistry Cardiac Biomarkers in the Identification of Future Risk in Chronic Obstructive Pulmonary Disease
Current Topics in Medicinal Chemistry A Focus on Heme Oxygenase-1 (HO-1) Inhibitors
Current Medicinal Chemistry The Frequency and Risk Factors of Diabetic Foot Ulcer Recurrence Among Jordanian Patients with Diabetes
Current Diabetes Reviews Current Pharmacological Treatment of Nonalcoholic Fatty Liver
Current Medicinal Chemistry Uric Acid and Diabetes: Is there a Link?
Current Pharmaceutical Design Obesity: Its Consequences Upon Respiratory System Function
Current Respiratory Medicine Reviews The Effect of Acute Hypoxia on Excitability in the Heart and the L-Type Calcium Channel as a Therapeutic Target
Current Drug Discovery Technologies COX-2 Selective Inhibitors in the Treatment of Arthritis: A Rheumatologist Perspective
Current Topics in Medicinal Chemistry Preface [Hot Topic: Cytochrome P450 and Diseases: Implications in Drug Metabolism and Pathophysiology (Guest Editor: Vincent Pichette)]
Current Drug Metabolism A Review of the Role of Statins in Heart Failure Treatment
Current Clinical Pharmacology Natriuretic Peptides as the Basis of Peptide Drug Discovery for Cardiovascular Diseases
Current Topics in Medicinal Chemistry Effect of an Angiotensin II Receptor Blocker and Two Angiotensin Converting Enzyme Inhibitors on Transforming Growth Factor-β (TGF-β) and α-Actomyosin (α SMA), Important Mediators of Radiation-Induced Pneumopathy and Lung Fibrosis
Current Pharmaceutical Design