Abstract
Polyhydroxyalkanoates (PHAs) and other biopolymers vary in their behavior and properties, but are extremely useful in medical applications because of their biodegradability. As long-term problems arise with permanent implants, different biopolymers can be selected and blended to replace the old PHAs and other homopolymers with new, less invasive alternatives. Scaffolds and surgical meshes are not designed to fuse with regrown tissue, but are intended to both guide new tissue and degrade when they are no longer required. The mechanical properties, characteristic length, and degradation profile of scaffold biopolymers are the key concerns in their medical application. Although the PHA and other biopolymers have excessively long degradation times, blending tough polymers with less durable polymers may alleviate the problems. The hydrophobic polymers must be balanced with their cytotoxicity; therefore, additional focus is being placed on changing the surface properties through grafting.
Keywords: Polyhydroxyalkanoates, mechanical property, scaffold, characteristic length, PHAs, PHB.
Graphical Abstract
Call for Papers in Thematic Issues
Active Alkaloids: Structure, Mechanism of Action, Chemical Synthesis, and Biosynthesis
The scope of this topic encompasses the structure, mechanism of action, chemical synthesis, and biosynthesis of active alkaloids. Alkaloids, a class of nitrogen-containing organic compounds with alkaline properties, originate from a diverse array of sources. Many alkaloids exhibit significant biological activities and serve as key constituents in numerous medicinal plants. ...read more
Advancement in Petroleum Geochemistry
The scope of the thematic issue on advancements in petroleum geochemistry encompasses a broad range of cutting-edge research and technological innovations. This issue aims to highlight the latest developments in understanding the chemical and physical properties of petroleum and its geological formations. Key areas of focus include: Unconventional Resources: Exploring ...read more
Advancements in Synthesis of Bioactive Compounds
This thematic issue focuses on elucidating advanced synthetic strategies for bioactive compounds, with the primary objective of deepening understanding of the rational design and construction of target molecules. The exploration encompasses a diverse range of techniques, established name reactions, and cutting-edge synthetic methodologies. Specifically, the issue delves into the synthesis ...read more
Advances in Sustainable Synthesis and Applications of Cyclic Carbonates: From Green Chemistry to Advanced Materials
Cyclic carbonates have become a focus of attention because of their potential in sustainable chemistry, energy solutions, and advanced materials. Recent breakthroughs in their synthesis emphasize the use of CO₂ as a renewable feedstock, which is a step toward reducing carbon emissions. New catalytic processes, including both traditional metal catalysts ...read more
Related Books
Ionic Liquids for Organic Synthesis
Glycals and their Derivatives
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
72
13
1