摘要
背景：巨噬细胞移动抑制因子（MIF）在20世纪60年代首次被描述为影响多种免疫细胞的多效性细胞因子。 已经报道了主要涉及诸如趋化因子样功能和调节全身应激反应的炎症反应的不同生理功能。 目的：在一些临床研究中，使用MIF作为生物标志物已被研究用于炎症方面的疾病如脓毒症，全身感染和自身免疫性疾病的有前景的支持。 本文详细回顾了临床数据并评估了作为关注炎症和自身免疫疾病的生物标志物的功能。 结论：最近的研究表明MIF是不同炎性疾病的标志物，并可能成为未来的治疗靶点。
关键词: MIF，生物标志物，感染性疾病，自身免疫性疾病，细胞因子，CD74，CXCR。
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