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Cardiovascular & Hematological Disorders-Drug Targets


ISSN (Print): 1871-529X
ISSN (Online): 2212-4063

Case Studies

The Intriguing Occurrence of Segmental Arterial Mediolysis: Case Report and Concise Literature Review

Author(s): Muhammad Ali Chaudhry *

Volume 17, Issue 2, 2017

Page: [74 - 79] Pages: 6

DOI: 10.2174/1871529X17666170703115833

Price: $65


Background: Segmental medial arteriolysis (SAM) is a unique arteriopathy highlighted by significant lytic changes in the medial wall of the blood vessels and can present from vague gastrointestinal discomfort to catastrophic abdominal bleeding and shock. We hereby present a concise review of this rare phenomenon with historic perspectives, epidemiology, and current concepts of etiology, pathogenesis, relevant clinical associations, treatment modalities, prognosis and future directions in SAM.

Conclusion: In addition, we present an interesting occurrence of this intriguing phenomenon in a forty-eight year old lady at our institution who presented with vague symptomatology and was an extremely challenging diagnosis. This highlights the importance of timely detection and institution of therapeutic or preventive strategies to minimize future catastrophic events.

Keywords: Intriguing, mediolysis, segmental arterial, arteriopathy, stenoses, hyperlipidemia.

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