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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances

Author(s): Luana da S. M. Forezi, Mariana F. C. Cardoso, Dora C. S. Costa, Fernando de C. da Silva and Vitor F. Ferreira*

Volume 14, Issue 5, 2017

Page: [375 - 390] Pages: 16

DOI: 10.2174/1570193X14666170518125507

Price: $65

Abstract

2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.

Keywords: Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions, napthoquinone.

Graphical Abstract

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