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Current Organic Synthesis

Editor-in-Chief

ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

Review Article

Oxazolidine- and Oxazoline-2-thiones: An Update

Author(s): Estibaliz Sansinenea*, Aurelio Ortiz, Patrick Rollin and Sandrina Silva*

Volume 14 , Issue 8 , 2017

Page: [1109 - 1131] Pages: 23

DOI: 10.2174/1570179414666170503165413

Price: $65

Abstract

Background: Sulfur-containing compounds are widespread among natural products and bioactive substances, and also useful ligands in asymmetric catalysis.

Objectives: In this context, different methods for the preparation of oxazolidine- and oxazoline-2-thiones and their more recent applications are reviewed.

Conclusions: In this survey, novel rearrangements and new reactions have also been summarized since 2007 until 2016.

Keywords: Oxazolidine-2-thiones, oxazoline-2-thiones, chiral auxiliary, applications, asymmetric synthesis, diastereoselectivity.

Graphical Abstract

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