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Current Traditional Medicine


ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

Review Article

A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)

Author(s): Mona Semalty, Lokesh Adhikari, Divya Semwal, Anita Chauhan, Akash Mishra, Rupali Kotiyal and Ajay Semalty*

Volume 3, Issue 3, 2017

Page: [156 - 167] Pages: 12

DOI: 10.2174/2215083803666170502120028

Price: $65


Background and Objective: Urtica dioica (stinging nettle), a member of the Urticaceae family, has been used in various traditional systems of medicines since ancient times especially for joint pain, arthritis and prostate problems. Its roots and leaves contain a wide variety of bioactive constituents like sterols, fatty acids, lectins terpenes, phenylpropanes, lignans and coumarins. The leaves and root extract shows various activities like hypoglycemic, anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic and antiviral activity. It shows its effects through the inhibition of aromatase, 5 α-reductase, cell proliferation and Na+, K+-ATPase inhibition.

Conclusion: The article reviews the phytochemistry and phytopharmacology of the plant.

Keywords: Alopecia, analgesic, anti-arthritic, antihypertensive, anti-inflammatory, 5 alpha reductase inhibitor, BPH, herbal remedy, nettle, urtica.

Graphical Abstract

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