Abstract
Skin is the most suitable and recommendable organ of the human body for topical administration and the main route for topical drug delivery system. Drug delivery system is the methodology used to ensure the entry of drugs into the body, reaching their target for pharmacological action. Patients tend to prefer the painless route for drug administration. So, pharmaceutical aerosols came to existence to meet patient compliance. Many variations in excipients with respect to compatibility to drugs, stability and economy are being used to improve the aerosol system of drug delivery. The present review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Summary: The review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Conclusion: Presently, aerosol drug delivery system has become beneficial as far as faster pharmacological action and economy are concerned. Other than the active pharmaceutical ingredient (API), the pharmacological action of the aerosol system is also dependent on the excipients used as they help the API to penetrate through the skin as fast as possible.
Keywords: Excipients, pharmaceutical aerosol, propellants, skin, solvents, topical drug delivery system.
Current Drug Delivery
Title:Importance of Propellants and Excipients in Pharmaceutical Topical Aerosol
Volume: 14 Issue: 8
Author(s): Maunab Patra*, Sibasis Bhattacharya and Meenakshi Patnaik
Affiliation:
- Abbess Healthcare OPC Pvt. Ltd., Kandivili East, Mumbai - 400101,India
Keywords: Excipients, pharmaceutical aerosol, propellants, skin, solvents, topical drug delivery system.
Abstract: Skin is the most suitable and recommendable organ of the human body for topical administration and the main route for topical drug delivery system. Drug delivery system is the methodology used to ensure the entry of drugs into the body, reaching their target for pharmacological action. Patients tend to prefer the painless route for drug administration. So, pharmaceutical aerosols came to existence to meet patient compliance. Many variations in excipients with respect to compatibility to drugs, stability and economy are being used to improve the aerosol system of drug delivery. The present review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Summary: The review deals with the excipients and constituents used in a pharmaceutical aerosol system as per target delivery.
Conclusion: Presently, aerosol drug delivery system has become beneficial as far as faster pharmacological action and economy are concerned. Other than the active pharmaceutical ingredient (API), the pharmacological action of the aerosol system is also dependent on the excipients used as they help the API to penetrate through the skin as fast as possible.
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Cite this article as:
Patra Maunab *, Bhattacharya Sibasis and Patnaik Meenakshi, Importance of Propellants and Excipients in Pharmaceutical Topical Aerosol, Current Drug Delivery 2017; 14 (8) . https://dx.doi.org/10.2174/1567201814666170309104245
DOI https://dx.doi.org/10.2174/1567201814666170309104245 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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