Abstract
Background: Metathesis reactions represent an attractive and powerful tool for the synthesis of new carbon-carbon double bonds. The development of ruthenium complexes allows to perform the transformation in both organic and polymer chemistry. Indenylidene catalysts constitute a very important part of this area, as they have been found to be resistant to harsh reaction conditions (temperature and presence of functional groups). In addition, thanks to their good catalytic activities they quickly became a mainstream catalysts in metathesis-type reactions in recent years.
Objective: In this Review we intend to give a general overview of indenylidene catalysts in a broad sense.
Conclusion: Synthesis and activity studies of modified first- and second-generation complexes as well as catalysts bearing pyridine or bidenate ligands are described herein. The application of indenylidene catalysts is discussed in light of both simple model reactions and synthesis of biologically active compounds.
Keywords: Metathesis, ruthenium catalysts, indenylidene catalysts, N-heterocyclic carbenes, simple model reactions.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
16
5
2
2