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Letters in Drug Design & Discovery

Editor-in-Chief

ISSN (Print): 1570-1808
ISSN (Online): 1875-628X

Review Article

A Brief Overview on Chemistry and Biology of Benzoxepine

Author(s): Naveen Kuntala, Jhonsee R. Telu, Jaya S. Anireddy and Sarbani Pal*

Volume 14, Issue 9, 2017

Page: [1086 - 1098] Pages: 13

DOI: 10.2174/1570180814666161227125227

Price: $65

Abstract

Background: The present review article is related to the synthesis and medicinal importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the branch of organic / medicinal chemistry and always attracts the attention of chemists working not only in the area of organic synthesis but also in natural products.

Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative, antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of this class of compounds.

Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.

Keywords: Benzoxepine, heterocycles, synthesis, medicinal importance, chemistry, biology.

Graphical Abstract

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