Abstract
Background: The present review article is related to the synthesis and medicinal importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the branch of organic / medicinal chemistry and always attracts the attention of chemists working not only in the area of organic synthesis but also in natural products.
Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative, antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of this class of compounds. Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.Keywords: Benzoxepine, heterocycles, synthesis, medicinal importance, chemistry, biology.
Letters in Drug Design & Discovery
Title:A Brief Overview on Chemistry and Biology of Benzoxepine
Volume: 14 Issue: 9
Author(s): Naveen Kuntala, Jhonsee R. Telu, Jaya S. Anireddy and Sarbani Pal*
Affiliation:
- Department of Chemistry, MNR Degree & PG College, Kukatpally, Hyderabad-500072,India
Keywords: Benzoxepine, heterocycles, synthesis, medicinal importance, chemistry, biology.
Abstract: Background: The present review article is related to the synthesis and medicinal importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the branch of organic / medicinal chemistry and always attracts the attention of chemists working not only in the area of organic synthesis but also in natural products.
Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative, antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of this class of compounds. Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.Export Options
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Cite this article as:
Kuntala Naveen, Telu R. Jhonsee, Anireddy S. Jaya and Pal Sarbani*, A Brief Overview on Chemistry and Biology of Benzoxepine, Letters in Drug Design & Discovery 2017; 14 (9) . https://dx.doi.org/10.2174/1570180814666161227125227
DOI https://dx.doi.org/10.2174/1570180814666161227125227 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
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