Protein Kinases as Drug Targets in Human and Animal Diseases

Title:Protein Kinases as Drug Targets in Human and Animal Diseases

Volume: 13 Issue: 2

Author(s): Suvarna G. Kini*, Vikas Garg, Sharada Prasanna, Revathi Rajappan and Muhammad Mubeen

Affiliation:

• Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka,India

Keywords: Cancer, inflammatory and autoimmune diseases, kinases, protein kinases.

Abstract: Almost thirty percent of the protein targets currently under exploration and study constitute the protein kinases which have always attracted the pharmaceutical companies as they are easy targets for drug development. Although the kinases will remain major focus of oncology for many years to come in the development of anticancer drugs, the number of kinase inhibitors as therapeutic targets for the treatment of several other diseases which are undergoing clinical trials are exponentially increasing. In this review, we discuss very briefly the different types of protein kinases that have been used as targets for developing drugs for cancer, inflammation, autoimmune disease, heart disease and animal diseases.

Cite this article as:

Kini G. Suvarna*, Garg Vikas, Prasanna Sharada, Rajappan Revathi and Mubeen Muhammad, Protein Kinases as Drug Targets in Human and Animal Diseases, Current Enzyme Inhibition 2017; 13 (2) . https://dx.doi.org/10.2174/1573408013666161128144216