Abstract
Background: Plants, including herbs and spices, have many phytochemicals which are a potential source of natural antioxidants e.g., phenolic diterpenes, flavonoids, alkaloids, tannins and phenolic acids. Various researches have been done to find out the relative antioxidant activities of various herbs, fruits, vegetables and spices.
Objectives: Present study was carried out to evaluate the antioxidant status of five common spices namely Brassica nigra (Rai), Foeniculum vulgare (Fennel), Carum copticum (Ajwain), Nigella sativa (Kalonji) and Sesamum indicum (Til). Methodology: In-vitro antioxidant study of these spices was examined by using the popular method of DPPH free radical scavenging activity and FRAP methods. The total phenolic compounds were measured using the Folin-Ciocalteu reagent in an effort to validate the medicinal potential of the spices. Results: The antioxidant activity of the methanolic extract of Brassica nigra (92.8%) was observed to be the highest followed by Foeniculum vulgare (91.8%), Carum copticum (89.7%), Nigella sativa (83.2%) while for Sesamum indicum, least antioxidant activity was recorded (38%). Their IC50 ranged from 4 mg/ml in Brassica nigra (Rai) to 8 mg/ml in Nigella sativa (Kalonji). Nitric oxide scavenging activity was highest in Rai (11%) and lowest in Til. The ferric reducing properties of the above spices were also found to be quite appreciable. Highest phenolic content (based on Folin’s Ciocalteau method) was shown by Carum copticum (18.1) whereas highest flavonoid content was recorded in Foeniculum vulgare (20.7). Conclusion: The significant presence of phenolic and flavonoid content revealed that the spices can be used as rich sources of natural antioxidants against various oxidative stress related disorders.Keywords: Spices, DPPH assay, phenolic content, flavonoid content, phytochemical.
Graphical Abstract
Call for Papers in Thematic Issues
Ayurvedic medicinal therapeutic approaches for inflammatory and neurodegenerative disorders
Usually, in our elderly population, neurodegenerative disorders occur due to neuron death. Alzheimer?s disease (AD) is an irreversible and progressive neurodegenerative disease. Dementia is the leading cause of AD, which affects about 30 million people worldwide. According to the World Alzheimer report 2018, a new case of dementia develops every ...read more
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
Related Journals
Anti-Cancer Agents in Medicinal Chemistry
Current Analytical Chemistry
Current Computer-Aided Drug Design
Current Bioactive Compounds
Combinatorial Chemistry & High Throughput Screening
Current Organic Chemistry
Current Medicinal Chemistry
Current Organic Synthesis
Central Nervous System Agents in Medicinal Chemistry
Mini-Reviews in Organic Chemistry
Related Books
Botanicals and Natural Bioactives: Prevention and Treatment of Diseases
Biosurfactants: A Boon to Healthcare, Agriculture & Environmental Sustainability
Frontiers in Computational Chemistry
Advances in Dye Degradation
Biological and Medical Significance of Chemical Elements
Frontiers In Medicinal Chemistry
Advances in Organic Synthesis
Frontiers in Natural Product Chemistry
Recent Advances in Analytical Techniques
Advanced Catalysts Based on Metal-organic Frameworks (Part 2)
27
2
1
1