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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

A Review on Injury Mechanism of Intracerebral Hemorrhage in Vehicle Accidents

Author(s): Fan Li*, Honggeng Li, Zhi Xiao, Ronggui Lu, Zhiteng Zhang, Haiyun Zhu and Lihai Ren

Volume 23, Issue 15, 2017

Page: [2177 - 2192] Pages: 16

DOI: 10.2174/1381612823666161118144829

Price: $65


Background: Intracerebral hemorrhage is one of the most common injuries in vehicle accidents. The aim of this paper is to survey the injury mechanism of intracerebral hemorrhage in vehicle accidents, including contusion, subarachnoid hemorrhage (SAH), subdural hematoma (SDH) and diffuse axonal injury (DAI).

Methods: A condensed overview is given based on the published studies in biomechanical studies on intracerebral hemorrhage. Animal tests, cadaver tests, accident investigations and numerical simulation are the main method used for the mechanism studies.

Results: Angular velocity and acceleration can be used to predict these injuries and they are the main causation of DAI. Intracranial pressure is the main causation of coup/contrecoup contusion. Shear stress and strain contribute to the rupture of bridging veins that result in SDH, SAH.

Conclusion: Injury mechanism of intracerebral hemorrhage in vehicle accidents is complicated that with multiple causations. In-depth works need to be carried out in mechanism studies especially for child head injuries.

Keywords: Intracerebral hemorrhage, brain injury, vehicle accident, passive safety, subarachnoid hemorrhage (SAH), subdural hematoma (SDH).

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