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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Algae Polysaccharides’ Chemical Characterization and their Role in the Inflammatory Process

Author(s): Noelia Florez, Maria Jesus Gonzalez-Munoz, Daniela Ribeiro, Eduarda Fernandes, Herminia Dominguez and Marisa Freitas

Volume 24, Issue 2, 2017

Page: [149 - 175] Pages: 27

DOI: 10.2174/0929867323666161028160416

Price: $65


Polysaccharides are abundant components in marine macroalgae with potential applications in different areas such as pharmaceutical, biomedical, cosmetics and nutrition. The current interest in these compounds is due to their known bioactivities, conferred by their antiallergic, neuroprotective, gastroprotective, cardioprotective, cytotoxic, anticoagulant/antithrombotic, antiviral, antilipidemic, antinociceptive, and immunomodulatory properties, making them promising bioactive products and biomaterials. The inflammatory process is a complex event mediated by the immune system that culminates in the neutralization and elimination of the offending insult protecting the host and restoring tissue homeostasis. This review focuses on the extraction procedures and chemical characterization of polysaccharides from different classes of algae (Phaeophyceae, Rhodophyceae and Chlorophyceae) and on the studies on their inflammatory process modulatory effect.

Keywords: Macroalgae, polysaccharides, inflammation, seaweed, brown algae, red algae, green algae.

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