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Current Cancer Drug Targets


ISSN (Print): 1568-0096
ISSN (Online): 1873-5576

Review Article

New Perspectives in Glioblastoma: Nanoparticles-based Approaches

Author(s): Rosa Luciano, Giulia Battafarano, Rossana Saracino, Michela Rossi, Antonio Perrotta, Melania Manco, Maurizio Muraca and Andrea Del Fattore

Volume 17, Issue 3, 2017

Page: [203 - 220] Pages: 18

DOI: 10.2174/1568009616666160813190732

Price: $65


Glioblastoma multiforme represents one of the most aggressive tumor of central nervous system. Current therapy includes surgery, radiation and chemotherapy. These treatments are rarely curative and glioma are associated with a poor prognosis. Nanomedicine represents the most innovative branch of medicine since many studies demonstrated great advantage in the diagnosis and therapy of several diseases. In this review we will summarize the results obtained by the use of nanoparticles and extracellular vesicles in glioblastoma. A great interest is raising from these studies that underlined the efficacy and specificity of this treatment for glioma, reducing side-effects associated with conventional therapies.

Keywords: Glioblastoma, nanomedicine, nanoparticles, extracellular vesicles.

Graphical Abstract

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