Abstract
The Diels-Alder (DA) reaction has been applied to the total synthesis of natural products. It can get good yields because of high stereoselectivity and regioselectivity. Herein, the DA reaction catalyzed by Lewis acids was introduced, and some total syntheses of natural products from 2013 to 2015 using DA reaction were also illustrated and analyzed.
Keywords: Diels-Alder reaction, Total synthesis, Applications.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
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