Generic placeholder image

Current Signal Transduction Therapy


ISSN (Print): 1574-3624
ISSN (Online): 2212-389X

Research Article

Classification of Malignant and Benign Micro Calcifications from Mammogram Using Optimized Cascading Classifier

Author(s): Natarajan Krishnamoorthy, Ramasamy Asokan and Isabella Jones

Volume 11, Issue 2, 2016

Page: [98 - 104] Pages: 7

DOI: 10.2174/1574362411666160614083720

Price: $65


Background: Breast cancers are one of the most prevalent forms of cancers amongst women apart from being the top second cause of cancer related deaths across the world. A way to detect the presence of breast cancers earlier is through the presence of minute deposits of calcium, that is, micro-calcifications in mammograms. Detecting this much earlier is important for successfully treating the cancer.

Method: In the current work, a novel Hybrid Particle Swarm Optimized (PSO) cascaded classifier is suggested. Wavelet Features linked to Histogram of Oriented Gradients (HOG) based features selection technique is utilized. For the detection of micro-calcifications utilizing the Support Vector Machines (SVM) is a supervised learning technique which may be utilized for classifications as well as regressions. Cascade classifications are capable of tackling all the mentioned challenges with an integrated model through the usage of asymmetric cascades of sparse classifiers, every single one trained to attain great detection sensitivities as well as adequate false positive rates.

Results: SVM-Poly kernels, SVM-Radial Basis Function (RBF) kernels, Cascaded classifiers, PSO optimized cascade classifiers as well as Hybrid PSO optimized cascade classifiers are valuated for classification accuracies, sensitivities as well as specificities. The suggested Hybrid PSO optimized cascade classifiers outperform all other in all categories. It was observed that the proposed Hybrid PSO optimized cascade classifier method increased classification accuracy by 2.49%-8.74%, compared with other methods.

Conclusion: Experimental evaluations proved the abilities of the suggested Hybrid PSO optimized cascade classifiers for the exploration of features space for best features combination for malignant and benign micro-calcifications from mammograms.

Keywords: Mammogram, breast cancer, microcalcifications, Histogram of Oriented Gradients (HOG), Support Vector Machines (SVM), cascaded classifier, Particle Swarm Optimization (PSO).

Graphical Abstract

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy