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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Development of Arene Ruthenium Antitumor Complexes

Author(s): Wei Su, Zhaofeng Tang and Peiyuan Li

Volume 16, Issue 10, 2016

Page: [787 - 795] Pages: 9

DOI: 10.2174/138955751610160503003937

Price: $65


The organometallic arene ruthenium complexes are rapidly advancing. In particular, the organoruthenium complexes of the type [(η6-arene)Ru(X)(Y)(Z)] have attracted increasing attention for their special structures and properties. This review is focused on the recent developments of [(η6- arene)Ru(X)(Y)(Z)]-typed complexes incorporating various biologically active ligands, which are important in the exploration of novel multi-targeted organometallic anticancer drugs.

Keywords: Anticancer agent, Arene, Biologically active ligands, Ruthenium.

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