Abstract
Various polyamide microcapsules were prepared via an inverse emulsion system (water in oil) by interfacial polycondensation of terephthaloyl dichloride with the aliphatic diamines ethylene diamine (EDA) and 1,6-hexane diamine (HMDA), and the aromatic diamine 1,4-phenylene diamine (PDA). Three types of polyamide microcapsules were thus obtained and labeled: CAPS EDA, CAPS HMDA, and CAPS PDA, respectively. The influence that the various substitutions had on particle size distribution, membrane microstructure, porosity and specific surface area and water content of the polyamide microcapsule was investigated. The roughness, porosity and porous volume of the polyamide membrane increased in the order: CAPS EDA < CAPS HMDA < CAPS PDA. Sodium chloride permeation experiments were performed to obtain an insight into the impact of structural changes on the permeability of the microcapsules to ionic species. The NaCl diffusion and permeability coefficients through the microcapsules were found to be in the order of 10-8 cm2 / s and 10-5 cm / s, respectively.
Keywords: interfacial polycondensation, microencapsulation, polyamide, diamine
Current Drug Delivery
Title: Influence of The Monomers Type on the Morphology of Polyamide Microcapsules
Volume: 1 Issue: 2
Author(s): Abohachem Laguecir, Mohamed Radhouan Louhaichi and Michel Burgard
Affiliation:
Keywords: interfacial polycondensation, microencapsulation, polyamide, diamine
Abstract: Various polyamide microcapsules were prepared via an inverse emulsion system (water in oil) by interfacial polycondensation of terephthaloyl dichloride with the aliphatic diamines ethylene diamine (EDA) and 1,6-hexane diamine (HMDA), and the aromatic diamine 1,4-phenylene diamine (PDA). Three types of polyamide microcapsules were thus obtained and labeled: CAPS EDA, CAPS HMDA, and CAPS PDA, respectively. The influence that the various substitutions had on particle size distribution, membrane microstructure, porosity and specific surface area and water content of the polyamide microcapsule was investigated. The roughness, porosity and porous volume of the polyamide membrane increased in the order: CAPS EDA < CAPS HMDA < CAPS PDA. Sodium chloride permeation experiments were performed to obtain an insight into the impact of structural changes on the permeability of the microcapsules to ionic species. The NaCl diffusion and permeability coefficients through the microcapsules were found to be in the order of 10-8 cm2 / s and 10-5 cm / s, respectively.
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Cite this article as:
Laguecir Abohachem, Louhaichi Radhouan Mohamed and Burgard Michel, Influence of The Monomers Type on the Morphology of Polyamide Microcapsules, Current Drug Delivery 2004; 1 (2) . https://dx.doi.org/10.2174/1567201043479984
DOI https://dx.doi.org/10.2174/1567201043479984 |
Print ISSN 1567-2018 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5704 |
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