摘要
急性肾衰竭(ARF)是恶性肿瘤的一种严重并发症,导致显著的发病率和死亡率。急性肾衰竭是一种常见的部分多器官功能障碍的危重患者报告的死亡率从72%癌症85%人需要肾脏替代治疗的患者。导致ARF的癌症患者的途径是ARF在其他条件的共同发展。然而,导致急性肾功能衰竭的发展的某些因素可能是肿瘤或肿瘤治疗相关。本综述的目的是在危重患者给肾脏疾病的具体方面(CICPs),概述CICPs的原因和ARF描述这些并发症的管理的最新进展,包括治疗的毒性和骨髓移植(BMT)。急性肾功能衰竭的预防是必须的,因此在CICPs ARF的可能的治疗方法进行了讨论。
关键词: 急性肾功能衰竭,肿瘤溶解综合征,肝细胞癌,多发性骨髓瘤,淋巴瘤。
Current Medicinal Chemistry
Title:Acute Renal Failure in Different Malignant Tumors
Volume: 23 Issue: 19
Author(s): Sanja Radojevic-Skodric, Ljiljana Bogdanovic, Milena Jovanovic, Ivana Baralic, Zoran Dzamic, Ron Gordon, Simona Ognjanovic and Gordana Basta-Jovanovic
Affiliation:
关键词: 急性肾功能衰竭,肿瘤溶解综合征,肝细胞癌,多发性骨髓瘤,淋巴瘤。
摘要: Acute renal failure (ARF) represents a severe complication of malignancies, that causes significant morbidity and mortality. ARF is a common part of multiple organ dysfunction in critically ill patients with cancer with reported mortality rates from 72% to 85% in patients who need renal replacement therapy. The pathways leading to ARF in cancer patients are common to the development of ARF in other conditions. However, certain factors leading to the development of ARF may be associated to the tumor or to the tumor therapy. The purpose of this review is to give specific aspects of renal disease in critically ill cancer patients (CICPs), to overview the causes of ARF in CICPs and to describe recent progress in the management of these complications, including treatment toxicity and bone marrow transplantation (BMT). The prevention of ARF is obligatory and therefore the possible treatments of ARF in CICPs are also discussed.
Export Options
About this article
Cite this article as:
Sanja Radojevic-Skodric, Ljiljana Bogdanovic, Milena Jovanovic, Ivana Baralic, Zoran Dzamic, Ron Gordon, Simona Ognjanovic and Gordana Basta-Jovanovic , Acute Renal Failure in Different Malignant Tumors, Current Medicinal Chemistry 2016; 23 (19) . https://dx.doi.org/10.2174/0929867323666160407113245
DOI https://dx.doi.org/10.2174/0929867323666160407113245 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
Approaches to the treatment of chronic inflammation
Chronic inflammation is a hallmark of numerous diseases, significantly impacting global health. Although chronic inflammation is a hot topic, not much has been written about approaches to its treatment. This thematic issue aims to showcase the latest advancements in chronic inflammation treatment and foster discussion on future directions in this ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Recent Developments in Protein and Cell-Targeted Aptamer Selection and Applications
Current Medicinal Chemistry Cutting Edge: Chemoprevention of Colorectal Neoplasia in Inflammatory Bowel Disease
Inflammation & Allergy - Drug Targets (Discontinued) Interplay between Epigenetics & Cancer Metabolism
Current Pharmaceutical Design Encountering and Advancing Through Antiangiogenesis Therapy for Gliomas
Current Pharmaceutical Design Physcion and Physcion 8-O-β-D-glucopyranoside: Natural Anthraquinones with Potential Anticancer Activities
Current Drug Targets Recent Advances in the Synthesis and Development of Curcumin, its Combinations and Formulations and Curcumin-like Compounds as Anti-infective Agents
Current Medicinal Chemistry Controlled Release of Plasmid DNA from Hyaluronan Nanoparticles
Current Drug Delivery Distinctive Phenotype Identification for Breast Cancer Genotypes Among Hereditary Breast Cancer Mutated Genes
Current Bioinformatics Ghrelin: New Insight to Mechanisms and Treatment of Postoperative Gastric Ileus
Current Pharmaceutical Design Platinum Compounds: A Hope for Future Cancer Chemotherapy
Anti-Cancer Agents in Medicinal Chemistry Biosynthetic Pathways to Glycosidase Inhibitors
Current Chemical Biology The Advance of Dendrimers - A Versatile Targeting Platform for Gene/Drug Delivery
Current Pharmaceutical Design Dasatinib: An Anti-Tumour Agent via Src Inhibition
Current Drug Targets P-Glycoprotein - Implications of Metabolism of Neoplastic Cells and Cancer Therapy
Current Cancer Drug Targets Epigallocatechin-3-gallate(EGCG): Mechanisms and the Combined Applications
Combinatorial Chemistry & High Throughput Screening Ferritin and Percent Transferrin Saturation Levels Predict Type 2 Diabetes Risk and Cardiovascular Disease Outcomes
Current Diabetes Reviews SnoN in TGF-β Signaling and Cancer Biology
Current Molecular Medicine Monoclonal Antibodies Targeting the Epidermal Growth Factor Receptor
Current Drug Targets Hypoxia Responsive Drug Delivery Systems in Tumor Therapy
Current Pharmaceutical Design Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer
Current Drug Metabolism