Abstract
Background: The clinical and therapeutic significance of dopamine, known as important hormone and neurotransmitter, motivated the development of the sensitive, rapid, and cost effective electrochemical methods for its determination.
Methods: This review comments on the advances in the electrochemical sensing and biosensing of dopamine, covering the period 2005-2015. Results: The electrocatalytic properties and analytical performances of the dopamine sensors based on: bare electrodes, electrochemically pretreated electrodes, chemically modified electrodes (CNTs-, graphene-, NPs-, MIPs, polymers-, and miscellaneous inorganic and organic materials-modified electrodes), as well as of the biosensors based on tyrosinase carbon nanomaterials-modified electrodes and tyrosinase polymersmodified electrodes are compared and discussed. The presented data demonstrate that the electrochemical sensors and biosensors based on CNTs- and graphene- modified electrodes exhibit better analytical performances compared with the other groups for the sensitive and respectively for the simultaneous or selective determination of dopamine in the presence of the interfering species ascorbic acid and uric acid. Conclusion: The overview of the literature reveals that sensitivity enhancement and in vivo measurements still remain the challenges in the development of the electrochemical sensors and biosensors for dopamine determination.Keywords: Dopamine, electrochemical sensors, electrochemical biosensors, chemically modified electrodes, MIPs, graphenemodified electrodes.
Current Analytical Chemistry
Title:Advances in the Electrochemical Analysis of Dopamine
Volume: 13 Issue: 2
Author(s): Margarita Stoytcheva*, Roumen Zlatev, Zdravka Velkova, Velizar Gochev, Gisela Montero, Lydia Toscano and Amelia Olivas
Affiliation:
- Engineering Institute, Autonomous University of Baja California, Mexicali,Mexico
Keywords: Dopamine, electrochemical sensors, electrochemical biosensors, chemically modified electrodes, MIPs, graphenemodified electrodes.
Abstract: Background: The clinical and therapeutic significance of dopamine, known as important hormone and neurotransmitter, motivated the development of the sensitive, rapid, and cost effective electrochemical methods for its determination.
Methods: This review comments on the advances in the electrochemical sensing and biosensing of dopamine, covering the period 2005-2015. Results: The electrocatalytic properties and analytical performances of the dopamine sensors based on: bare electrodes, electrochemically pretreated electrodes, chemically modified electrodes (CNTs-, graphene-, NPs-, MIPs, polymers-, and miscellaneous inorganic and organic materials-modified electrodes), as well as of the biosensors based on tyrosinase carbon nanomaterials-modified electrodes and tyrosinase polymersmodified electrodes are compared and discussed. The presented data demonstrate that the electrochemical sensors and biosensors based on CNTs- and graphene- modified electrodes exhibit better analytical performances compared with the other groups for the sensitive and respectively for the simultaneous or selective determination of dopamine in the presence of the interfering species ascorbic acid and uric acid. Conclusion: The overview of the literature reveals that sensitivity enhancement and in vivo measurements still remain the challenges in the development of the electrochemical sensors and biosensors for dopamine determination.Export Options
About this article
Cite this article as:
Stoytcheva Margarita*, Zlatev Roumen, Velkova Zdravka, Gochev Velizar, Montero Gisela, Toscano Lydia and Olivas Amelia, Advances in the Electrochemical Analysis of Dopamine, Current Analytical Chemistry 2017; 13 (2) . https://dx.doi.org/10.2174/1573411012999160401130209
DOI https://dx.doi.org/10.2174/1573411012999160401130209 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
Call for Papers in Thematic Issues
Advancements in biomedicine, corrosion inhibition/monitoring, and lubrication of carbon dots
Carbon dots, a class of carbon-based nanomaterials, have garnered substantial interest in various scientific and engineering fields due to their unique properties, including excellent optical properties, outstanding biocompatibility, easy preparation, good dispersity, ultrasmall size, low toxicity and environmental friendliness. This special issue of Current Analytical Chemistry aims to showcase cutting-edge ...read more
Applications of artificial intelligence in chemical analysis
Artificial intelligence (AI) has demonstrated its versatility in almost all scientific fields, especially analytical chemistry, which is leading the way in the integration of AI. According to Chemical Abstract Services, one of the major disciplines contributing to AI-related publications and patents is analytical chemistry. That?s because techniques such as deep ...read more
Bioanalytical and Biosensor Technologies for Target Molecules
Bioanalytical and biosensor technologies constitute the core of detecting and sensing diverse molecules within living organisms, encompassing proteins, DNA, small molecular metabolites, and beyond. These molecules assume pivotal roles in biological processes, rendering their analysis and sensing indispensable for comprehending biological phenomena and unraveling disease mechanisms. In the current landscape ...read more
Biogeochemistry: global environmental research and management
his issue focuses on the bio-pathways of trace elements (Ni, Co, Cr, Mn, Cd, Pb, Zn and REE) in soil, plant and atmospheric systems. Specific interest in the application of phytotechnologies that utilise hyperaccumulator plants (agro/phytomining). On the basis of understanding the migration and transformation of trace elements in ecosystem, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Autonomic Nervous System Alterations in Rett Syndrome
Current Pediatric Reviews Meet Our Editorial Board Member
Current Neuropharmacology Novel Nucleic Acid-Based Agents: siRNAs and miRNAs
Central Nervous System Agents in Medicinal Chemistry Editorial (Hot Topic: Epidemiology & Risk Factors for Alzheimer’s Disease)
Current Alzheimer Research The Cold Case of Metabotropic Glutamate Receptor 6: Unjust Detention in the Retina?
Current Neuropharmacology Role of Chymase in Preeclampsia
Current Vascular Pharmacology Myocardial Revascularization for the Elderly: Current Options, Role of Off-pump Coronary Artery Bypass Grafting and Outcomes
Current Cardiology Reviews Chronic Effects of Cocaine on Dopaminergic and Serotonergic Systems of Rats
Current Molecular Imaging (Discontinued) Association Analysis of Genetic Variants of the Serotonin and Dopamine System-regulated Genes in Methamphetamine Abusers
Applied Clinical Research, Clinical Trials and Regulatory Affairs Monoclonal Antibodies: A Review
Current Clinical Pharmacology In Vitro Antioxidant Activity of Some Novel Synthetic Mononuclear Ruthenium (II) Compounds
Letters in Drug Design & Discovery Regulation of Blood Flow by Prostaglandins
Current Vascular Pharmacology EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs
Current Gene Therapy Modulation of the Maturing Gut Barrier and Microbiota: A Novel Target in Allergic Disease
Current Pharmaceutical Design Nanoparticle-Based Combination Therapy for Cancer Treatment
Current Pharmaceutical Design Nanomaterial Based Approaches for the Diagnosis and Therapy of Cardiovascular Diseases
Current Pharmaceutical Design The Molecular Targets of Antitumor 2-deoxycytidine Analogues
Current Drug Targets Models to Study Atherosclerosis: A Mechanistic Insight
Current Vascular Pharmacology Neurotoxicity and Side-Effects of Highly Active Antiretroviral Therapy [HAART] on the Central and Peripheral Nerve System
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Obsessive-compulsive Disorder with Comorbid Bipolar Disorders: Clinical Features and Treatment Implications
Current Medicinal Chemistry