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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Applications of Dimedone in the Synthesis of Heterocycles: An Update

Author(s): Majid M. Heravi, Vahideh Zadsirjan, Bahareh Fattahi and Niousha Nazari

Volume 20, Issue 16, 2016

Page: [1676 - 1735] Pages: 60

DOI: 10.2174/1385272820666160324154001

Price: $65


Dimedone (5,5-dimethylcyclohexane-1,3-dione) is an alicyclic diketone, occasionally considered as building blocks in design and synthesis of a wide variety of heterocycles. The synthetic efficacy of dimedone as a synthon has been presented as a chapter in Advances in Heterocyclic Chemistry in 2009. Due to importance of dimedone and huge numbers of cited references concerning its applications after 2009 till date, in this review we try to update its unique role as a privileged synthon in the synthesis of different heterocyclic compounds.

Keywords: Dimedone, heterocycles, multicomponent reaction, alicyclic diketone.

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