Abstract
Background: The debate on whether sex-specific predictive models improve risk stratification after myocardial infarction is ongoing. Methods: This review summarises the current clinical knowledge on sex-specific differences in post-infarction risk stratification parameters. Particular focus is given to electrocardiographic risk factors and indices of cardiac autonomic status. Results: Differences in the underlying pathophysiology between men and women are known. However, clinical findings often lead to uncertain conclusions for a number of risk predictors including, among others, resting heart rate, heart rate variability, heart rate turbulence, QT interval duration, and QRS-T angle. The review links recent findings in prognostic parameters with successful approaches in sex-specific non-invasive risk stratification. Conclusion: Disparities are described in the current clinical opinions on the relevance of investigated parameters in women and possible directions for further research in the field are given.
Keywords: Women, heart rate, heart rate variability, heart rate turbulence, baroreflex sensitivity, QT width, QRS T-angle, AMI.
Current Pharmaceutical Design
Title:Electrocardiographic and Cardiac Autonomic Indices - Implications of Sex-Specific Risk Stratification in Women After Acute Myocardial Infarction
Volume: 22 Issue: 25
Author(s): Romy Ubrich, Petra Barthel, Anna Berkefeld, Katerina Hnatkova, Katharina M Huster, Michael Dommasch, Daniel Sinnecker, Alexander Steger, Georg Schmidt and Marek Malik
Affiliation:
Keywords: Women, heart rate, heart rate variability, heart rate turbulence, baroreflex sensitivity, QT width, QRS T-angle, AMI.
Abstract: Background: The debate on whether sex-specific predictive models improve risk stratification after myocardial infarction is ongoing. Methods: This review summarises the current clinical knowledge on sex-specific differences in post-infarction risk stratification parameters. Particular focus is given to electrocardiographic risk factors and indices of cardiac autonomic status. Results: Differences in the underlying pathophysiology between men and women are known. However, clinical findings often lead to uncertain conclusions for a number of risk predictors including, among others, resting heart rate, heart rate variability, heart rate turbulence, QT interval duration, and QRS-T angle. The review links recent findings in prognostic parameters with successful approaches in sex-specific non-invasive risk stratification. Conclusion: Disparities are described in the current clinical opinions on the relevance of investigated parameters in women and possible directions for further research in the field are given.
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Ubrich Romy, Barthel Petra, Berkefeld Anna, Hnatkova Katerina, Huster M Katharina, Dommasch Michael, Sinnecker Daniel, Steger Alexander, Schmidt Georg and Malik Marek, Electrocardiographic and Cardiac Autonomic Indices - Implications of Sex-Specific Risk Stratification in Women After Acute Myocardial Infarction, Current Pharmaceutical Design 2016; 22 (25) . https://dx.doi.org/10.2174/1381612822666160311115605
DOI https://dx.doi.org/10.2174/1381612822666160311115605 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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