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Mini-Reviews in Medicinal Chemistry


ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Synthesis and Biological Activities of Oxadiazole Derivatives: A Review

Author(s): Ankur Vaidya, Shweta Jain, Priyanka Jain, Prachi Jain, Nidhi Tiwari, Roshni Jain, Rashi Jain, Abhishek K. Jain and Ram K. Agrawal

Volume 16, Issue 10, 2016

Page: [825 - 845] Pages: 21

DOI: 10.2174/1389557516666160211120835

Price: $65


Recently, there has been wide interest in compounds containing the oxadiazole scaffold because of their unique chemical structure and their broad spectrum of biological properties. This review provides readers with an overview of the main synthetic methodologies for oxadiazoles and of their broad spectrum of pharmacological activities such as, anti-microbial, anti-fungal activity, antiviral, anti-tubercular, anti-inflammatory, anti-convulsant, anti-angiogenic, anti-proliferative, analgesic, anti-oedema and in alzheimer activity, which were reported over the past years.

Keywords: Anti-bacterial, anticonvulsant, antifungal, anti-inflammatory, analgesic, anticancer, oxadiazole.

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