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Current Drug Targets


ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

Secondary Prevention of Ischemic Stroke

Author(s): Kirsi Rantanen and Turgut Tatlisumak

Volume 5, Issue 5, 2004

Page: [457 - 472] Pages: 16

DOI: 10.2174/1389450043345425

Price: $65


Stroke strikes often suddenly, causes long-term disability and death, and is a huge economical burden for the society, not to mention the human tragedy for the patient and the family. At least 15% of stroke survivors will have a second stroke during the next five years, quarter of which prove out to be fatal within four weeks [1]. Secondary prevention of ischemic stroke (IS) targets at reducing stroke recurrence by means of 1) detection and modification of risk factors, 2) antithrombotic or anticoagulant treatment, and 3) surgical interventions for selected patient subgroups. In this review we will discuss these issues in detail and also offer our personal suggestions for treatment choices. Detecting and treating the modifiable risk factors is the major challenge of secondary prevention of IS.

Keywords: stroke, prevention, cerebrovascular disease, risk factors, antithrombotic agents, brain infarct, endarterectomy

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