Abstract
In this review, we tried to highlight the recent advances in the Biginelli reaction, leading to the synthesis of 3,4-dihydropyrimidin-2(1H)-ones, albeit only those conducted under microwave irradiation. The merits and drawbacks of these reactions are compared and discussed with those performed under conventional heating.
Dedicated to kazem Kargosha, in the occasion of his honorable retirement as a Professor in Analytical Chemistry. I would like to open this essay by paying homage to Professor Kargosha, who was much inspirational to the establishment of the Iranian Chemical &Chemical Engineering Society (then, Iranian Chemical Society).
Keywords: Biginelli reaction, dihydropyrimidines, DHPMs microwave irradiation, brønsted acid, lewis acid, ionic liquid, catalysis, multicomponent reactions, (MCRs).
Current Organic Synthesis
Title:Microwave-Assisted Biginelli Reaction: An Old Reaction, a New Perspective
Volume: 13 Issue: 4
Author(s): Majid M. Heravi, Mahdieh Ghavidel and Bahareh Heidari
Affiliation:
Keywords: Biginelli reaction, dihydropyrimidines, DHPMs microwave irradiation, brønsted acid, lewis acid, ionic liquid, catalysis, multicomponent reactions, (MCRs).
Abstract: In this review, we tried to highlight the recent advances in the Biginelli reaction, leading to the synthesis of 3,4-dihydropyrimidin-2(1H)-ones, albeit only those conducted under microwave irradiation. The merits and drawbacks of these reactions are compared and discussed with those performed under conventional heating.
Dedicated to kazem Kargosha, in the occasion of his honorable retirement as a Professor in Analytical Chemistry. I would like to open this essay by paying homage to Professor Kargosha, who was much inspirational to the establishment of the Iranian Chemical &Chemical Engineering Society (then, Iranian Chemical Society).
Export Options
About this article
Cite this article as:
Heravi M. Majid, Ghavidel Mahdieh and Heidari Bahareh, Microwave-Assisted Biginelli Reaction: An Old Reaction, a New Perspective, Current Organic Synthesis 2016; 13 (4) . https://dx.doi.org/10.2174/1570179413666151218202307
DOI https://dx.doi.org/10.2174/1570179413666151218202307 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
Call for Papers in Thematic Issues
Advances on New Photochromic Compounds. Synthesis and Applications
Photochromic compounds are materials that can reversibly change color or optical properties when exposed to light, typically ultraviolet (UV) or visible light. This reversible color change is due to a molecular rearrangement or isomerization triggered by light absorption. Advances in this field are focused on synthesizing photochromic compounds with faster ...read more
Biorthogonal Chemistry: A translational Chemical Tool for In Vivo Applications
After the discovery in 1990, bioorthogonal chemistry encompassed a set of diverse, fast-paced selective chemical reactions, facilitating the study of biomolecules under physiological aura without intervening in the biochemical processes. Over the past two decades, significant progress has been witnessed in bioorthogonal reactions such as Staudinger ligation, metal-catalyzed coupling reactions, ...read more
Design and Synthesis of Green Pesticides
The development of new green pesticides is currently one of the hotspots in the field of pesticide research, aiming to develop efficient, environmentally friendly, and safe pesticide products to meet the needs of modern agricultural production. New green pesticides prioritize environmental friendliness and ecological safety. Therefore, during the research and ...read more
Design and Synthesis of Novel Green Pesticides
The increasing need for sustainable agriculture has driven the search for novel, environmentally friendly alternatives to conventional chemical pesticides. This thematic issue explores the design and synthesis of novel green pesticides that are super-efficient, non-toxic and residue-free. Emphasizing the development of bio-based and eco-friendly pesticides, the issue highlights cutting-edge research ...read more
Related Journals

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers