Nitric Oxide Synthases and Their Natural Inhibitors

Title:Nitric Oxide Synthases and Their Natural Inhibitors

Volume: 12 Issue: 1

Author(s): Christos Kontogiorgis and Dimitra Hadjipavlou-Litina

Affiliation:

Keywords: Nitric oxide synthase inhibitors, naturally occurring NOS inhibitors, NOS inhibitors from plants, isolated natural compounds, extracts from plants.

Abstract: Nitric Oxide (NO) is a molecule of extreme interest to biologists, pharmacologists, physiologists, and biochemists, characterized as a mediator in the cardiovascular system. It has been found to be implicated in various pathological processes. NO is synthesized enzymatically by Nitric Oxide Synthases (NOSs) from L-arginine, and therefore NOSs have emerged as very crucial therapeutic targets. Herein, a series of extracts from plants as well as a number of isolated compounds acting as NOS inhibitors are presented.

Cite this article as:

Kontogiorgis Christos and Hadjipavlou-Litina Dimitra, Nitric Oxide Synthases and Their Natural Inhibitors, Current Enzyme Inhibition 2016; 12 (1) . https://dx.doi.org/10.2174/1573408012666151126185628