Umbilical Cord is a Rich Source of Mesenchymal Stromal Cells for Cell Therapy

Title:Umbilical Cord is a Rich Source of Mesenchymal Stromal Cells for Cell Therapy

Volume: 11 Issue: 8

Author(s): Tokiko Nagamura-Inoue and Takeo Mukai

Affiliation:

Keywords: Cryopreservation, explant, immunosuppression, mesenchymal stromal cells, stem cell therapy, umbilical cord.

Abstract: Recently, umbilical cord (UC) and UC-derived mesenchymal stromal cells (UC-MSCs) have attracted much attention for many reasons, including (1) abundant sources and ease of collection, storage, and transport; (2) little ethical controversy; (3) multipotency to differentiate into various cell types; and (4) low immunogenicity with significant immunosuppressive ability. In this review, we provide a brief introduction to UC and UC-MSCs in terms of characteristics, isolation, and cryopreservation, as well as emphasizing their potential clinical application in regenerative medicine and immunotherapy.

Cite this article as:

Nagamura-Inoue Tokiko and Mukai Takeo, Umbilical Cord is a Rich Source of Mesenchymal Stromal Cells for Cell Therapy, Current Stem Cell Research & Therapy 2016; 11 (8) . https://dx.doi.org/10.2174/1574888X10666151026115017