Generic placeholder image

Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Nano-Systems for Advanced Therapeutics and Diagnosis of Atherosclerosis

Author(s): Chauhan Gaurav, Bhandari Saurav, Rath Goutam and Amit K. Goyal

Volume 21, Issue 30, 2015

Page: [4498 - 4508] Pages: 11

DOI: 10.2174/1381612821666150917094215

Price: $65


Cardiovascular diseases (CVDs) are the leading cause of death and morbidity worldwide. Atherosclerotic situations such as acute myocardial infarction(MI) and stroke are still major causes of death worldwide. Present therapeutic approaches based on conventional drug delivery systems are not efficient to control these disorders. With the technological advancement and intervention of nanotechnology, several fascinating areas are explored for the management of these disorders. Targeted drug delivery approaches and diagnostic tools presented by nanotechnology, certainly took the atherosclerotic disease management to next level. Criticality lies in the rationale selection of an appropriately designed nanocarrier for targeting a specific zone of disease. Manuscript provides a descriptive view of disease targets; nanotechnology based therapeutic and diagnostic approaches and different nanocarriers to accomplish this task. It is important to have the understanding of different classes of these nanosystems along with their specific merits and demerits. Mechanisms and approaches for improving the selectivity or targeting potential are also discussed. There is no doubt that nanotechnology is having great impact in this area, but it is equally important to rationalize its scale up aspects for a real world success.

Keywords: Cardiovascular diseases, atherosclerosis, nanosystems, drug delivery, diagnosis, targeting.

Rights & Permissions Print Export Cite as
© 2024 Bentham Science Publishers | Privacy Policy