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Current Drug Delivery


ISSN (Print): 1567-2018
ISSN (Online): 1875-5704

Use of Nanotechnology in Diagnosis and Treatment of Hepatic Fibrosis: A Review

Author(s): Somayeh Taymouri and Azade Taheri

Volume 13, Issue 5, 2016

Page: [662 - 672] Pages: 11

DOI: 10.2174/1567201812666150907115404

Price: $65


Liver fibrosis is an important cause of morbidity and mortality worldwide and represent a difficult clinical challenge of global importance. The liver fibrosis progression needs to be controlled because persisted liver fibrosis can lead to liver cirrhosis or even hepatocellular carcinoma. Despite significant advances in the understanding of the liver fibrosis development, the therapeutic effect of drugs used in liver fibrosis treatment is not sufficient. Today, nanotechnology has been considered as a potential tool for developing novel drug delivery systems for the improved imaging and various diseases, including liver fibrosis. In this article, we discussed the use of nanotechnology for the treatment and imaging of liver fibrosis.

Keywords: Antifibrotic therapy, antiviral therapy, hepatic stellate cells, liver fibrosis, nanotechnology, siRNA.

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