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Current Organic Synthesis


ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

New Ideas for a 160 Years-Old Reaction

Author(s): Gabriela F. Mendonça, Leonardo S. de Almeida, Marcio C.S. de Mattos, Pierre M. Esteves and Rodrigo S. Ribeiro

Volume 12 , Issue 5 , 2015

Page: [603 - 617] Pages: 15

DOI: 10.2174/157017941205150821130712

Price: $65


Haloarenes are important chemical compounds from academic, biological, and industrial point of view. They can usually be prepared by an electrophilic halogenation of aromatic compounds using the halogen in its elemental form (X2), a reaction formerly described by Couper in 1857. Recently, the interest in new reagents that can accomplish a safe, efficient, and convenient halogenation of arenes has grown enormously. The present review summarizes the utilization of trihaloisocyanuric acids in the electrophilic aromatic halogenations and focuses on their green aspects.

Keywords: Arenes, electrophilic reactions, green chemistry, halogenation, N-halo compounds, trihaloisocyanuric acids.

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