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Current Bioactive Compounds


ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Investigations into the Chemistry and Insecticidal Activity of Euonymus europaeus Seed Oil and Methanol Extract

Author(s): Juergen Wanner, Nurhayat Tabanca, Martin Zehl, Leopold Jirovetz, Erich Schmidt, Andreas Patschka, Abbas Ali, Alden S. Estep, James J. Becnel, Andrew Y. Li and Ikhlas A. Khan

Volume 11, Issue 1, 2015

Page: [13 - 22] Pages: 10

DOI: 10.2174/157340721101150804142925

Price: $65


Euonymus europaeus seeds and seed oil were investigated for their volatiles using GC-MS-FID and Headspace- SPME/GC-MS-FID, and for their non-volatile compounds using derivative GC-MS-FID and HPLC-DADCAD/ MS. The seeds contain about 30% of fatty oil, mainly glyceryl trioleate, small amounts of abietadiene and -triene, dihydroagarofurane sesquiterpenes, and alkaloids of the sesquiterpene pyridine type. Breakdown products of the latter can be found by transesterification with tetramethylammonium hydroxide. In the seed oil, glyceryl acetates are slowly formed through cleavage of alkaloids and triglycerides. Bioassay results indicated both the seed oil and methanol extract had weak repellent and larvicidal activity against the yellow fever mosquito (Aedes aegypti), and were ineffective in repelling the long star tick (Amblyomma americanum) at the concentrations tested.

Keywords: Aedes aegypti and Amblyomma americanum, Euonymus europaeus L., insecticidal activity, GC-MS-FID, LC-MS, methanol extract, seed oil, SPME.

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